68 results found for "immunotherapy"
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article
Pioneering Progress in Cancer Immunotherapy
Single-cell genomics advances T cell immunotherapies at MD Anderson Cancer Center …
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Society for Immunotherapy of Cancer
SITC 2016 …
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Publications
Novel technologies and emerging biomarkers for personalized cancer immunotherapy
The culmination of over a century’s work to understand the role of the immune system in tumor control has led to the recent advances in cancer immunotherapies that have resulted in durable clinical responses in patients with a variety of malignancies. …
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Publications
Successful immunotherapy induces previously unidentified allergen-specific CD4+ T-cell subsets
Allergen immunotherapy can desensitize even subjects with potentially lethal allergies, but the changes induced in T cells that underpin successful immunotherapy remain poorly understood. …
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Publications
A Prospective Clinical Trial Combining Radiation Therapy With Systemic Immunotherapy in Metastatic Melanoma
Local radiation therapy (RT) combined with systemic anti-cytotoxic T-lymphocyte-associated protein-4 immunotherapy may enhance induction of systemic antimelanoma immune responses. …
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article
Webinar | Towards an assay of global immune competence
Holden Maecker discusses the need to develop a global assay of immunocompetence …
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A Visionary Call to Action
Sonia Gavasso on the potential for mass cytometry to improve immunotherapy …
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Getting the Whole Pathology Picture
David Rimm on the value of Imaging Mass Cytometry for immunology applications at Yale …
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6th Annual Mass Cytometry Summit Recap
The recent Summit in Boston was our largest and most informative yet …
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Publications
CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a high medical need disease with limited treatment options. …
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CyTOF Interest Group Meeting
Join us at Washington University and discover the latest in mass cytometry. …
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Unraveling the Biology of Cancer
Bernd Bodenmiller on revealing new insights into tumors with Imaging Mass Cytometry …
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Publications
SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: Online resources and useful tools - a compass in the land of biomarker discovery
Recent positive clinical results in cancer immunotherapy point to the potential of immune-based strategies to provide effective treatment of a variety of cancers. …
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Publications
Expression of CCL21 in Ewing sarcoma shows an inverse correlation with metastases and is a candidate target for immunotherapy
Ewing sarcoma is an aggressive neoplasm predominantly occurring in adolescents and has a poor prognosis when metastasized. …
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Publications
Checkpoint blockade immunotherapy reshapes the high-dimensional phenotypic heterogeneity of murine intratumoural neoantigen-specific CD8+ T cells
The analysis of neoantigen-specific CD8+ T cells in tumour-bearing individuals is challenging due to the small pool of tumour antigen-specific T cells. …
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article
On Phenotype and Function
Deeply profile T cell checkpoint response with mass cytometry immuno-oncology panels …
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Publications
Immunotherapy-induced sarcoidosis in patients with melanoma treated with PD-1 checkpoint inhibitors: Case series and immunophenotypic analysis
Sarcoidosis is a multisystem granulomatous disease. …
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media
Webinar | Defining the phenotypic and functional immune microenvironment in AML
Evan Lind describes his work to deeply profile the immune cell landscape in AML …
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Publications
Characterization of the first-in-class T-cell-engaging bispecific single-chain antibody for targeted immunotherapy of solid tumors expressing the oncofetal protein claudin 6
The fetal tight junction molecule claudin 6 (CLDN6) is virtually absent from any normal tissue, whereas it is aberrantly and frequently expressed in various cancers of high medical need. …
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Publications
Monitoring the Immune Competence of Cancer Patients to Predict Outcome
A new era of cancer immunotherapy has brought not only successful cancer vaccines but also immunomodulators, such as those that target checkpoint blockade in order to induce endogenous host immune responses. …