40 results found for "epigenetics"
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article
ATAC-Seq
How Will Greenleaf, ATAC-seq and C1 Open App are pioneering single-cell epigenetics …
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Press Release
SINGLE-CELL EPIGENETICS COMES TO THE FLUIDIGM C1™ SYSTEM
Available Free on Fluidigm's Single-Cell Community Web Portal - Script Hub™ …
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Publications
Epigenetics modifications and Subclinical Atherosclerosis in Obstructive Sleep Apnea: The EPIOSA study
Obstructive sleep apnea (OSA) is associated with increased risk for cardiovascular morbidity and mortality. …
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article
Developing Bimodal Single-Cell Omics
Stanford’s Ansu Satpathy designed single-cell T-ATAC-seq, now available at Script Hub …
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article
What’s New for C1 Applications on Script Hub
View the growing list of community-developed apps for single-cell biology …
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article
The Single-Cell Analysis Technologist
Burroughs Wellcome Fund honors Charles Gawad’s genomics mission for pediatric biology …
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resource
Script Hub
Script Hub™ is your central source for C1™ methods and applications. Get access to scripts and other applications developed by Fluidigm and the C1 community, including epigenetics, mRNA sequencing, DNA sequencing, cell staining and more.
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media
Single Cell Genomics 2015
sometimes the sum of the parts is greater than the whole …
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article
Script Hub
Breakthrough single-cell applications developed by and for the C1 community …
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Publications
EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas
Several signaling pathways important for the proliferation and growth of brain cells are pathologically dysregulated in gliomas, including the epidermal growth factor receptor (EGFR). …
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Publications
Inefficient Reprogramming of Fibroblast into Cardiomyocytes Using Gata4, Mef2c, and Tbx5
Direct reprogramming of fibroblasts into cardiomyocytes is a novel strategy for cardiac regeneration. However, the key determinants involved in this process are unknown. …
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event
Single Cell Genomics 2016
The Whole is Other than the Sum of the Parts …
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Publications
Divergent RNA-Binding Proteins, DAZL and VASA, Induce Meiotic Progression in Human Germ Cells Derived In Vitro
Our understanding of human germ cell development is limited in large part due to inaccessibility of early human development to molecular genetic analysis. …
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Publications
A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood
Many recent epigenetic studies report that cigarette smoking reduces DNA methylation in whole blood at the single CpG site cg19859270 within the GPR15 gene. …
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Publications
Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity
Obesity is associated with immunological perturbations that contribute to insulin resistance. …
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Publications
Oocyte-specific linker histone H1foo is an epigenomic modulator that decondenses chromatin and impairs pluripotency
Mammalian oocytes contain the histone H1foo, a distinct member with low sequence similarity to other members in the H1 histone family. …
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Publications
Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer
Cancer is as much an epigenetic disease as a genetic one; however, the interplay between these two processes is unclear. …
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Publications
A rapid passage through a two-active-X-chromosome state accompanies the switch of imprinted X-inactivation patterns in mouse trophoblast stem cells
In female mice, while the presence of two-active X-chromosomes characterises pluripotency, it is not tolerated in most other cellular contexts. …
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Publications
Lineage-specific regulation of imprinted X inactivation in extraembryonic endoderm stem cells
Silencing of the paternal X chromosome (Xp), a phenomenon known as imprinted X-chromosome inactivation (I-XCI), characterises, amongst mouse extraembryonic lineages, the primitive endoderm and the extraembryonic endoderm (XEN) stem cells derived from it. …
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Publications
Genome-wide epigenomic profiling for biomarker discovery
A myriad of diseases is caused or characterized by alteration of epigenetic patterns, including changes in DNA methylation, post-translational histone modifications, or chromatin structure. …