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5503 results found

  • consumable

    Anti-Mouse CD49d/Integrin α4 (R1-2)-151Eu—100 Tests

    CD49d, also known as α4 integrin or VLA-4 α chain, is an integrin chain that forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7) and binds to VCAM-1, MadCAM-1, fibronectin, and collagens. …

    Product #: 3151016B

  • consumable

    Anti-Mouse CD140b (APB5)-151Eu—100 Tests

    CD140b, also known as platelet-derived growth factor receptor β (PDGFR-β), is a cell surface tyrosine kinase receptor and is expressed on embryonic tissues and mesenchymal-derived cells in adult mice. …

    Product #: 3151017B

  • consumable

    Anti-Human TNFa (Mab11)-152Sm—100 Tests

    Tumor necrosis factor (TNF)-alpha is a cytokine that plays a role in the acute inflammatory response to infections and has cytolytic activity against tumor cells. …

    Product #: 3152002B

  • consumable

    Anti-Human CD13 (WM15)-152Sm—100 Tests

    CD13, also known as aminopeptidase N, APN and gp150, is a 150–170 kDa transmembrane ectoenzyme occurring on monocytes and granulocytes but not lymphocytes in blood. …

    Product #: 3152003B

  • consumable

    Anti-Mouse CD3e (145-2C11)-152Sm—100 Tests

    CD3ε is a 20 kDa subunit of the TCR complex and is required for proper assembly, trafficking, and surface expression of the TCR complex. …

    Product #: 3152004B

  • consumable

    Anti-pAkt [S473] (D9E)-152Sm—50 Tests

    Akt, also known as PKB or Rac, is an intracellular serine/threonine protein kinase critically involved in several pathways including apoptosis, cell cycle, and energy regulation. …

    Product #: 3152005A

  • consumable

    Anti-Human CD36 (5-271)-152Sm—100 Tests

    CD36, also known as GPIIIb or GPIV, is an integral membrane glycoprotein and member of the class B scavenger receptor family of cell surface proteins. …

    Product #: 3152007B

  • consumable

    Anti-Human TCRgd (11F2)-152Sm—100 Tests

    The γ/δ T cell receptor, which is expressed on 5% of T cells, is involved in the recognition of certain bacterial, self-CD1 molecule, and tumor antigens bound to MHC class I. …

    Product #: 3152008B

  • consumable

    Anti-Human CD21 (BL13)-152Sm—100 Tests

    CD21, also known as CR2, is a 145 kDa transmembrane complement receptor expressed primarily on B cells, where it is found in complex with other membrane proteins that promote normal humoral and cellular immune responses. …

    Product #: 3152010B

  • consumable

    Anti-Human CD66b (80H3)-152Sm—100 Tests

    CD66b (CEACAM8) is a member of the human carcinoembryonic antigen (CEA) family. CD66b is exclusively expressed on human granulocytes and used as a marker of granulocyte activation. …

    Product #: 3152011B

  • consumable

    Anti-Human CD328/Siglec-7 (194211)-152Sm—100 Tests

    CD328, also known as sialic acid binding immunoglobulin-like lectin 7 (Siglec-7), is primarily expressed on the surface of NK cells and monocytes. …

    Product #: 3152013B

  • consumable

    Anti-Human cleaved Caspase 7 (D6H1)-152Sm—50 Tests

    Caspase-7, a member of the caspase (cysteine aspartate protease) family of proteins, has been shown to be an executioner protein of apoptosis upon cell death stimuli. …

    Product #: 3152014A

  • consumable

    Anti-Human CD45RA (HI100)-153Eu—100 Tests

    CD45RA is a specific splice variant of the transmembrane tyrosine phosphatase CD45. The CD45RA isoform is most highly expressed on resting/naive T cells, B cells and monocytes. …

    Product #: 3153001B

  • consumable

    Anti-Mouse CD45.1 (A20)-153Eu—100 Tests

    The CD45.1 isoform of CD45 is specific to certain mouse genetic backgrounds, and cells of that lineage can be identified with clone A20. …

    Product #: 3153002B

  • consumable

    Anti-pStat1 [Y701] (58D6)-153Eu—50 Tests

    STAT1 is a transcription factor involved in the response to multiple cytokines including IFNa, IFNg, IL-6, LIF, EGF, PDGF, and others. STAT1 is activated by phosphorylation at Tyr701 by JAK family members upon cytokine receptor engagement. …

    Product #: 3153003A

  • consumable

    Anti-Human CD62L (DREG-56)-153Eu—100 Tests

    CD62L, also known as L-selectin, is involved in immune cell homing and is expressed on naive T cells, most B cells, most thymocytes, and subsets of memory T cells, NK cells, monocytes, and granulocytes. …

    Product #: 3153004B

  • consumable

    Anti-pStat1 [Y701] (4a)-153Eu—50 Tests

    STAT1 is a transcription factor involved in the response to multiple cytokines including IFNa, IFNg, IL-6, LIF, EGF, PDGF, and others. STAT1 is activated by phosphorylation at Tyr701 by JAK family members upon cytokine receptor engagement. …

    Product #: 3153005A

  • consumable

    Anti-Mouse CD335/NKp46 (29A1.4)-153Eu—100 Tests

    CD335 is an activating receptor expressed uniquely on NK cells within the bone marrow and blood, allowing discrimination of NK cells and NKT cells. …

    Product #: 3153006B

  • consumable

    Anti-Human CD303/BDCA2 (201A)-153Eu—100 Tests

    CD303, also known as blood dendritic cell antigen 2 (BDCA-2), is the most specific marker for human pDC and is only expressed in humans. …

    Product #: 3153007B

  • consumable

    Anti-Human TIM-3 (F38-2E2)-153Eu—100 Tests

    TIM-3 is a type I transmembrane receptor that is constitutively expressed at high levels on NK cells. It is also expressed on specific subsets of CD4+ and CD8+ T cells, on subpopulations of macrophages and DCs, and on monocytes. …

    Product #: 3153008B