c-myc protein is a 62 kDa transcription factor that binds to DNA and activates transcription as part of a heterodimeric complex with Max. c-myc is a very strong proto-oncogene that is involved in cell growth, apoptosis, metabolism and tumorigenesis. Aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal and endocrine cells, as well as hematopoietic neoplasms. The 9E10 monoclonal antibody recognizes human myc and the 10 amino acid epitope tag of human c-myc.
Anti-Human c-Myc p67 (9E10)-164Dy—25 µg