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Anti-Mouse RORgt (B2D)-159Tb—100 Tests

RORγ (retinoid-related orphan receptor gamma) is a member of the nuclear hormone receptor family, NR1 subfamily. RORγ has 2 isoforms: γ1 and γ2 (also referred to as RORγt). The RORγt differs from RORγ1 isoform by lacking 3 unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the RORγ and RORγt isoforms. RORγt is expressed exclusively in only 2 cell populations, DP thymocytes and lymphoid tissue inducers (LTi). RORγt is essential for lymph nodes and Peyer's patches development and plays a critical role in control of apoptosis during thymopoiesis and T cell homeostasis.

  • Species:
    Mouse
  • Clone:
    B2D
  • Target:
    ROR gamma/t
  • Tag:
    159Tb

 

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