This antibody recognizes the human high-affinity Fc receptor for IgE (Fc epsilon RI), which plays a key role in the IgE-mediated allergic immune response. FceRI is a tetramer composed of one alpha, one beta and two gamma subunits. The AER-37 monoclonal antibody reacts with the FceRIα subunit, an IgE-binding subunit lacking signal-transducing ability. FceRIα is primarily found on mast cells and basophils and is upregulated by the presence of IgE.
Anti-Human FceRl (AER-37 (CRA-1))-150Nd—100 Tests