CD16, also known as low-affinity IgG receptor III (FcγRIII), is a polypeptide-anchored transmembrane protein. The CD16a isoform is expressed on the surface of NK cells, activated monocytes, macrophages and placental trophoblasts. CD16a mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. The CD16b isoform is expressed specifically on neutrophils. This clone was derived with a CD16a immunogen that has high homology to CD16b, and it is expected to recognize both isoforms.
Anti-Human CD16 (EPR16784)-146Nd—25 µg