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What is TraCeR analysis?

TraCeR is a tool developed by scientists at the EMBL-European Bioinformatics Institute and the Wellcome Trust Sanger Institute that reconstructs the sequences of rearranged and expressed T cell receptor (TCR) genes from single-cell mRNA sequencing data. It then uses the TCR sequences to identify cells that have the same receptor sequences and so derive from the same original clonally expanded cell. Find directions for setting up and using TraCeR on Script Hub™ or GitHub.