Charting a map through the cellular reprogramming landscape
Wen, L., Tang, F.
Analysis of the molecular mechanisms underlying somatic cell reprogramming into iPSCs is hampered by low efficiency of conversion and resulting cellular heterogeneity. In this issue of Cell Stem Cell, Zunder et al. (2015) utilize mass cytometry to perform high-throughput, single-cell analyses and provide a detailed molecular roadmap of the reprogramming process.
Wen, L., Tang, F. "Charting a map through the cellular reprogramming landscape" Cell Stem Cell (2016): 215–6